James B. Herrick described the sickle-cell disease in 1904.
Linus Pauling’s finding, in 1949, was the first to link a
genetic disease to a mutation of a specific protein. In 1954,
Vernon Ingram showed that the DNA of sickle-cell haemogloblin
varied from normal haemogloblin by one amino-acid, only one letter
in the DNA code. Except for bone-marrow transplants for children,
there is no cure for sickle-cell disease.
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