Nerve impulses

1952 Nerve impulses

The book of science

Tom Sharp

Alan Lloyd Hodgkin, Andrew Huxley neuroscience

Nerve impulses

Squid giant axon


Positive-charged sodium ions from outside of the cell membrane exchange positions with negative-charged potassium ions from inside. This exchange propagates in a fraction of a millisecond from the neuron to the axon terminal. Hodgkin and Huxley managed to measure this extremely fast event using voltage clamps on the giant axon of squid. Later, Andrew Huxley was the first to describe how muscles contract.

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